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GABA_A receptor function is regulated by lipid bilayer elasticity
Rikke Søgaard
, Thomas Werge
, Camilla Berthelsen
, C Lundbye
, K Madsen
,
Claus Helix Nielsen
, M B Andersen
, J A Lundbæk
Department of Physics
Psykiatrisk Center Sct Hans
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peer-review
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Keyphrases
Lipid Bilayer Elasticity
100%
Receptor Function
100%
GABAA Receptor (GABAAR)
100%
Docosahexaenoic Acid
62%
Muscimol
62%
Polyunsaturated Fatty Acids
25%
Receptor Desensitization
25%
Octyl
25%
β-glucoside
25%
Capsaicin
25%
Semi-quantitative Analysis
12%
Membrane Cholesterol
12%
Peak Amplitude
12%
Binding Capacity
12%
Expected Change
12%
Quantitative Relationship
12%
Whole-cell Voltage Clamp
12%
Host Lipids
12%
Force Transducer
12%
High-affinity Binding
12%
Spontaneous Curvature
12%
Equilibrium Binding Constant
12%
Mammalian Cells
12%
Biochemistry, Genetics and Molecular Biology
GABAA Receptor
100%
Muscimol
62%
Binding Affinity
25%
Receptor down Regulation
25%
Whole Cell
12%