Futuristic Aspects of Human Organ on a Chip

Martin Dufva*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review


The futuristic human organ on a chip (HOOC) is going to replace experimental animals, but many basic functions need to be implemented to reach that goal. Today, it is possible to keep 10-13 connected organs alive for 1-3 weeks without losing a significant function in most of the organs in the system. This number of organs is sufficient to model a large part of the basic physiology of an organism. Selecting which cell models to use and how to scale these models relative to each other to best mimic an organism is still not obvious and will be the research for the next decade. However, the road to that is long and will involve engineering better hardware solutions, obtaining more knowledge about the interplay between organs and tissue, and developing better and more accessible cell models.

Original languageEnglish
Title of host publicationMicrofluidics and Multi Organs on Chip
Publication date2022
ISBN (Print)978-981-19-1378-5
ISBN (Electronic)978-981-19-1379-2
Publication statusPublished - 2022


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