Fungal depside, guisinol, from a marine derived strain of Emericella unguis

Joan Nielsen, Per Halfdan Nielsen, Jens Christian Frisvad

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    A marine isolate of the fungus Emericella unguis gave a new antibacterial depside, guisinol (1). The structure determination was based on mass spectrometry and NMR spectroscopical studies. Structurally 1 resembles the depsidones emeguisin A --> C previously isolated from another strain of the same species. Five other isolates of E. unguis also produced the same qualitative profile of secondary metabolites including guisinol and dechloronidulin. Other species of Emericella did not produce any of these compounds and they are thus of chemotaxonomic significance. (C) 1998 Elsevier Science Ltd. All rights reserved.
    Original languageEnglish
    Issue number2
    Pages (from-to)263-265
    Publication statusPublished - 1999

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