Functionalized ormosil scaffolds processed by direct laser polymerization for application in tissue engineering

A. Matei, Jørgen Schou, Stela Canulescu, M. Zamfirescu, C. Albu, B. Mitu, E. C. Buruiana, T. Buruiana, C. Mustaciosu, I. Petcu, M. Dinescu

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Synthesized N,N′-(methacryloyloxyethyl triehtoxy silyl propyl carbamoyl-oxyhexyl)-urea hybrid methacrylate was polymerized by direct laser polymerization using femtosecond laser pulses with the aim of using it for subsequent applications in tissue engineering. The as-obtained scaffolds were modified either by low pressure argon plasma treatment or by covering the structures with two different proteins (lysozyme, fibrinogen). For improved adhesion, the proteins were deposited by matrix assisted pulsed laser evaporation technique. The functionalized structures were tested in mouse fibroblasts culture and the cells morphology, proliferation, and attachment were analyzed.
Original languageEnglish
JournalApplied Surface Science
Volume278
Pages (from-to)357–361
ISSN0169-4332
DOIs
Publication statusPublished - 2013
EventE-MRS 2012 Spring Meeting - Strasbourg, France
Duration: 14 May 201218 May 2012

Conference

ConferenceE-MRS 2012 Spring Meeting
CountryFrance
CityStrasbourg
Period14/05/201218/05/2012

Keywords

  • Ormosil scaffolds
  • Direct laser writing
  • Low pressure plasma treatment
  • MAPLE

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