Functionalized Ormosil Scaffolds Processed by Direct Laser Polymerization for Application in Tissue Engineering

A. Matei; Jørgen Schou; Stela Canulescu; M. Zamfirescu; C. Albu; B. Mitu; E. C. Buruiana; T. Buruiana; C. Mustaciosu; I. Petcu; M. Dinescu

Functionalized Ormosil Scaffolds Processed by Direct Laser Polymerization for Application in Tissue Engineering

A. Matei, Jørgen Schou, Stela Canulescu, M. Zamfirescu, C. Albu, B. Mitu, E. C. Buruiana, T. Buruiana, C. Mustaciosu, I. Petcu, M. Dinescu

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Abstract

The N,N’-(methacryloyloxyethyl triehtoxy silyl propyl carbamoyl-oxyhexyl)-urea hybrid methacrylate for applications in tissue engineering was synthesized and afterwards polymerized by direct laser polymerization using femtosecond laser pulses with the aim of using it for further applications in tissue engineering. The as-obtained scaffolds were modified either by low pressure argon plasma treatment or by using two different proteins (lysozyme, fibrinogen). For improved adhesion, the proteins were deposited by matrix assisted pulsed laser evaporation. The functionalized structures were tested in L929 mouse fibroblasts culture and the cells morphology, proliferation, and attachment were analyzed.

Original language	English
Publication date	2012
Number of pages	1
Publication status	Published - 2012
Event	E-MRS 2012 Spring Meeting - Strasbourg, France Duration: 14 May 2012 → 18 May 2012

Conference

Conference	E-MRS 2012 Spring Meeting
Country/Territory	France
City	Strasbourg
Period	14/05/2012 → 18/05/2012

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title = "Functionalized Ormosil Scaffolds Processed by Direct Laser Polymerization for Application in Tissue Engineering",

abstract = "The N,N{\textquoteright}-(methacryloyloxyethyl triehtoxy silyl propyl carbamoyl-oxyhexyl)-urea hybrid methacrylate for applications in tissue engineering was synthesized and afterwards polymerized by direct laser polymerization using femtosecond laser pulses with the aim of using it for further applications in tissue engineering. The as-obtained scaffolds were modified either by low pressure argon plasma treatment or by using two different proteins (lysozyme, fibrinogen). For improved adhesion, the proteins were deposited by matrix assisted pulsed laser evaporation. The functionalized structures were tested in L929 mouse fibroblasts culture and the cells morphology, proliferation, and attachment were analyzed.",

author = "A. Matei and J{\o}rgen Schou and Stela Canulescu and M. Zamfirescu and C. Albu and B. Mitu and Buruiana, {E. C.} and T. Buruiana and C. Mustaciosu and I. Petcu and M. Dinescu",

year = "2012",

language = "English",

note = "E-MRS 2012 Spring Meeting ; Conference date: 14-05-2012 Through 18-05-2012",

}

TY - ABST

T1 - Functionalized Ormosil Scaffolds Processed by Direct Laser Polymerization for Application in Tissue Engineering

AU - Matei, A.

AU - Schou, Jørgen

AU - Canulescu, Stela

AU - Zamfirescu, M.

AU - Albu, C.

AU - Mitu, B.

AU - Buruiana, E. C.

AU - Buruiana, T.

AU - Mustaciosu, C.

AU - Petcu, I.

AU - Dinescu, M.

PY - 2012

Y1 - 2012

N2 - The N,N’-(methacryloyloxyethyl triehtoxy silyl propyl carbamoyl-oxyhexyl)-urea hybrid methacrylate for applications in tissue engineering was synthesized and afterwards polymerized by direct laser polymerization using femtosecond laser pulses with the aim of using it for further applications in tissue engineering. The as-obtained scaffolds were modified either by low pressure argon plasma treatment or by using two different proteins (lysozyme, fibrinogen). For improved adhesion, the proteins were deposited by matrix assisted pulsed laser evaporation. The functionalized structures were tested in L929 mouse fibroblasts culture and the cells morphology, proliferation, and attachment were analyzed.

AB - The N,N’-(methacryloyloxyethyl triehtoxy silyl propyl carbamoyl-oxyhexyl)-urea hybrid methacrylate for applications in tissue engineering was synthesized and afterwards polymerized by direct laser polymerization using femtosecond laser pulses with the aim of using it for further applications in tissue engineering. The as-obtained scaffolds were modified either by low pressure argon plasma treatment or by using two different proteins (lysozyme, fibrinogen). For improved adhesion, the proteins were deposited by matrix assisted pulsed laser evaporation. The functionalized structures were tested in L929 mouse fibroblasts culture and the cells morphology, proliferation, and attachment were analyzed.

M3 - Conference abstract for conference

T2 - E-MRS 2012 Spring Meeting

Y2 - 14 May 2012 through 18 May 2012

ER -

Functionalized Ormosil Scaffolds Processed by Direct Laser Polymerization for Application in Tissue Engineering

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