Functional characterization of the saccharopine dehydrogenase LYS1 from filamentous fungi relevant for solid-state plant food fermentation

The escalating global population is challenging the food industry. Solid-state fungal fermentation of plant materials has emerged as a promising approach to enhance the amino acid profile and digestibility of more sustainable plant-based foods. This study focuses on LYS1, the enzyme catalyzing the final step in the synthesis of lysine through the fungal α-aminoadipate pathway, and comprises the identification, expression and characterization of the activity of LYS1 from relevant filamentous fungi.