Free-standing biomimetic polymer membrane imaged with atomic force microscopy

Christian Rein, Kamila Justyna Pszon-Bartosz, Karin Bagger Stibius Jensen, Thomas Bjørnholm, Claus Helix Nielsen

Research output: Contribution to journalJournal articleResearchpeer-review


Fluid polymeric biomimetic membranes are probed with atomic force microscopy (AFM) using probes with both normal tetrahedrally shaped tips and nanoneedle-shaped Ag2Ga rods. When using nanoneedle probes, the collected force volume data show three distinct membrane regions which match the expected membrane structure when spanning an aperture in a hydrophobic scaffold. The method used provides a general method for mapping attractive fluid surfaces. In particular, the nanoneedle probing allows for characterization of free-standing biomimetic membranes with thickness on the nanometer scale suspended over 300-μm-wide apertures, where the membranes are stable toward hundreds of nanoindentations without breakage. © 2010 American Chemical Society.
Original languageEnglish
Issue number2
Pages (from-to)499-503
Publication statusPublished - 2011


  • Biomimetic membrane
  • General method
  • Membranes
  • Fluid surface
  • Probes
  • Biomimetics
  • Functional polymers
  • Force-volume
  • Nano-meter scale
  • Nanoneedles
  • Gallium
  • Atomic force microscopy
  • Nanoindentation
  • Flexible structures
  • Biomimetic polymers
  • Polymers


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