Fouling kinetics in microfiltration of protein solutions using different membrane configurations

Sune Jakobsen, Gunnar Eigil Jonsson

Research output: Book/ReportBook


Protein fouling in microfiltration has a large impact on the permeate flux and observed retention of the proteins despite the fact that the protein molecule is several times smaller than the average pore size in microfiltration membranes. This is due to adsorption and deposition of protein molecules and aggregates. The effect of membrane configuration upon protein fouling was investigated in crossflow filtration with asymmetric membranes either in a normal mode or in a reverse mode. It was observed by Jonsson et al. [1] that beer filtration in a reverse mode results in a smaller decrease in the flux compared to beer filtration in a normal mode. Similar results for protein filtration were observed by Bowen et al. [2]. One possible way to avoid fouling is the novel backshock technique (see Jonsson et al. [1]). The effect of backshock on protein filtration was investigated using a hollow fiber module.
Original languageEnglish
Number of pages3
Publication statusPublished - 1997
EventConference of the European Membrane Society '97 - Twente, Netherlands
Duration: 23 Jun 199727 Jun 1997


ConferenceConference of the European Membrane Society '97

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