Formation of imines by selective gold-catalysed aerobic oxidative coupling of alcohols and amines under ambient conditions

Søren Kegnæs, Jerrik Jørgen Mielby, Uffe Vie Mentzel, Claus H. Christensen, Anders Riisager

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The formation of imines by aerobic oxidative coupling of mixtures of alcohols and amines was studied using gold nanoparticles supported on titanium dioxide, TiO2, as a heterogeneous catalyst. The reactions were performed at ambient conditions (room temperature and atmospheric pressure) and occurred with excellent selectivity (above 98%) at moderate conversion under optimized conditions. The effect of catalytic amounts of different bases was studied, along with reaction temperature and time. Utilisation of a selective catalyst system that uses dioxygen as an oxidant and only produces water as by-product represents a new green reaction protocol for imine formation.
Original languageEnglish
JournalGreen Chemistry
Volume12
Pages (from-to)1437-1441
ISSN1463-9262
DOIs
Publication statusPublished - 2010

Cite this

@article{1ee254929c5140009f99c56ea8c57811,
title = "Formation of imines by selective gold-catalysed aerobic oxidative coupling of alcohols and amines under ambient conditions",
abstract = "The formation of imines by aerobic oxidative coupling of mixtures of alcohols and amines was studied using gold nanoparticles supported on titanium dioxide, TiO2, as a heterogeneous catalyst. The reactions were performed at ambient conditions (room temperature and atmospheric pressure) and occurred with excellent selectivity (above 98{\%}) at moderate conversion under optimized conditions. The effect of catalytic amounts of different bases was studied, along with reaction temperature and time. Utilisation of a selective catalyst system that uses dioxygen as an oxidant and only produces water as by-product represents a new green reaction protocol for imine formation.",
author = "S{\o}ren Kegn{\ae}s and Mielby, {Jerrik J{\o}rgen} and Mentzel, {Uffe Vie} and Christensen, {Claus H.} and Anders Riisager",
year = "2010",
doi = "10.1039/c0gc00126k",
language = "English",
volume = "12",
pages = "1437--1441",
journal = "Green Chemistry",
issn = "1463-9262",
publisher = "Royal Society of Chemistry",

}

Formation of imines by selective gold-catalysed aerobic oxidative coupling of alcohols and amines under ambient conditions. / Kegnæs, Søren; Mielby, Jerrik Jørgen; Mentzel, Uffe Vie; Christensen, Claus H.; Riisager, Anders.

In: Green Chemistry, Vol. 12, 2010, p. 1437-1441.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Formation of imines by selective gold-catalysed aerobic oxidative coupling of alcohols and amines under ambient conditions

AU - Kegnæs, Søren

AU - Mielby, Jerrik Jørgen

AU - Mentzel, Uffe Vie

AU - Christensen, Claus H.

AU - Riisager, Anders

PY - 2010

Y1 - 2010

N2 - The formation of imines by aerobic oxidative coupling of mixtures of alcohols and amines was studied using gold nanoparticles supported on titanium dioxide, TiO2, as a heterogeneous catalyst. The reactions were performed at ambient conditions (room temperature and atmospheric pressure) and occurred with excellent selectivity (above 98%) at moderate conversion under optimized conditions. The effect of catalytic amounts of different bases was studied, along with reaction temperature and time. Utilisation of a selective catalyst system that uses dioxygen as an oxidant and only produces water as by-product represents a new green reaction protocol for imine formation.

AB - The formation of imines by aerobic oxidative coupling of mixtures of alcohols and amines was studied using gold nanoparticles supported on titanium dioxide, TiO2, as a heterogeneous catalyst. The reactions were performed at ambient conditions (room temperature and atmospheric pressure) and occurred with excellent selectivity (above 98%) at moderate conversion under optimized conditions. The effect of catalytic amounts of different bases was studied, along with reaction temperature and time. Utilisation of a selective catalyst system that uses dioxygen as an oxidant and only produces water as by-product represents a new green reaction protocol for imine formation.

U2 - 10.1039/c0gc00126k

DO - 10.1039/c0gc00126k

M3 - Journal article

VL - 12

SP - 1437

EP - 1441

JO - Green Chemistry

JF - Green Chemistry

SN - 1463-9262

ER -