Fluorescence enhancement of single DNA molecules confined in Si/SiO2 nanochannels

F. Westerlund, Karl Fredrik Persson, Anders Kristensen, J.O. Tegenfeldt

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    We demonstrate that the detected emission intensity from YOYO-labeled DNA molecules confined in 180 nm deep Si/SiO2 nano-funnels changes significantly and not monotonically with the width of the funnel. This effect may be of importance for quantitative fluorescence microscopy and for experiments with a tight photon budget.
    Original languageEnglish
    JournalLab on a Chip
    Volume10
    Issue number16
    Pages (from-to)2049-2051
    ISSN1473-0197
    DOIs
    Publication statusPublished - 2010

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