Abstract
Herein a reliable approach to the design of effective fluorescent probes for RNA detection is described. The fluorescence signalling of hybridization by internally positioned polyaromatic hydrocarbons and rhodamine dyes was achieved with a low fluorescence background signal, high fluorescence quantum yields at ambient and elevated temperature, high selectivity and signal specificity of the probes when binding to miR-7 and circRNA targets.
| Original language | English |
|---|---|
| Journal | R S C Advances |
| Volume | 4 |
| Issue number | 86 |
| Pages (from-to) | 45653-45656 |
| Number of pages | 4 |
| ISSN | 2046-2069 |
| DOIs | |
| Publication status | Published - 2014 |
| Externally published | Yes |