Fluid path system for dissolution and transport of a hyperpolarized material

John A. Urbahn (Inventor), Jan Henrik Ardenkjær-Larsen (Inventor), Andrew Michael Leach (Inventor)

Research output: Patent

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Abstract

A fluid path system (10) includes a vial (28) containing a frozen pharmaceutical product (12). A dissolution fluid path (36) is also included in the fluid path system (10), the dissolution fluid path (36) having an output end (42) in fluid communication with the vial (28) and an input end (38) attached to a pressure vessel (32) containing a dissolution medium (34). A delivery fluid path (44) has a first end (46) hermetically attached to the vial (28) to transport therefrom a mixture of dissolved pharmaceutical product (12) and dissolution medium (34) and a second end (50) connected to a receiving vessel (55) to receive the mixture.; A dissolution fluid path valve (40) is positioned between the pressure vessel (32) and the dissolution fluid path (36) to control flow of the dissolution medium (34), and a delivery fluid path valve (52) is also included in the fluid path system (10) to control flow of the mixture from the delivery fluid path (44) to the receiving vessel (55).

Original languageEnglish
IPCB01L99/00; G01N1/00
Patent numberGB2448054
Filing date01/10/2008
CountryUnited Kingdom
Priority date28/03/2007
Priority numberUS20070692642
Publication statusPublished - 2008

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