Abstract
Background - n-3 Polyunsaturated fatty acids (PUFA) are thought to affect immune function and may affect immune maturation in early life.
Objective - To examine if fish oil supplementation in late infancy could modify immune function.
Design - A 2×2 intervention with fish oil (3.4 ± 1.1 ml/day) or no fish oil and cow’s milk or infant formula from 9 to 12 month of age in 64 healthy Danish infants. Before and after the intervention we measured the fatty acid composition of erythrocyte (RBC) membranes, plasma IgE levels, C-reactive protein and soluble IL-2 receptors (sIL-2R) as well as cytokine production in whole-blood cultures stimulated with lipopolysaccharide (LPS)/phytohaemaglutinin (PHA) or Lactobacillus paracasei for 22 h. IgA was measured in feces at 10 months of age.
Results - Fish oil supplementation effectively raised RBC n-3 PUFA (p
| Original language | English |
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| Publication date | 2006 |
| Publication status | Published - 2006 |
| Event | Novel Aspects of Fatty Acids - Ystad, Sweden Duration: 1 Jan 2006 → … |
Conference
| Conference | Novel Aspects of Fatty Acids |
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| City | Ystad, Sweden |
| Period | 01/01/2006 → … |