Fish oil affects immune function in 9 to 12 month old infants

Camilla Trab Damsgaard, Lotte Lauritzen, Tanja Kjær, Hanne Frøkiær

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    Abstract

    Background - n-3 Polyunsaturated fatty acids (PUFA) are thought to affect immune function and may affect immune maturation in early life. Objective - To examine if fish oil supplementation in late infancy could modify immune function. Design - A 2×2 intervention with fish oil (3.4 ± 1.1 ml/day) or no fish oil and cow’s milk or infant formula from 9 to 12 month of age in 64 healthy Danish infants. Before and after the intervention we measured the fatty acid composition of erythrocyte (RBC) membranes, plasma IgE levels, C-reactive protein and soluble IL-2 receptors (sIL-2R) as well as cytokine production in whole-blood cultures stimulated with lipopolysaccharide (LPS)/phytohaemaglutinin (PHA) or Lactobacillus paracasei for 22 h. IgA was measured in feces at 10 months of age. Results - Fish oil supplementation effectively raised RBC n-3 PUFA (p
    Original languageEnglish
    Publication date2006
    Publication statusPublished - 2006
    EventNovel Aspects of Fatty Acids - Ystad, Sweden
    Duration: 1 Jan 2006 → …

    Conference

    ConferenceNovel Aspects of Fatty Acids
    CityYstad, Sweden
    Period01/01/2006 → …

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