First principles pharmacokinetic modeling: A quantitative study on Cyclosporin

Pharmacology, Toxicology and Pharmaceutical Science

• Bioaccumulation 50%
• Biodistribution 100%
• Ciclosporin 100%
• Clinical Trial 50%
• Drug Action 50%
• Drug Development 50%
• Elimination 50%
• Immunosuppressive Agent 50%
• Pharmacokinetic Modeling 100%
• Pharmacokinetic Parameter 50%
• Pharmacokinetics 100%
• Sprague Dawley Rat 50%

Keyphrases

• Biochemical Metabolism 50%
• Drug Biodistribution 50%
• Drug Mechanism of Action 50%
• Hepatic Clearance 50%
• Human Pharmacokinetics 50%
• Knowledge Gain 50%
• Model-informed Drug Development 50%