Filamentous Fungi Fermentation

Anders Nørregaard, Stuart Stocks, John Woodley, Krist Gernaey

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review


Filamentous fungi (including microorganisms such as Aspergillus niger and Rhizopus oryzae) represent an enormously important platform for industrial fermentation. Two particularly valuable features are the high yield coefficients and the ability to secrete products. However, the filamentous morphology, together with non-Newtonian rheological properties (shear thinning), result in poor oxygen transfer unless sufficient energy is provided to the fermentation. While genomic research may improve the organisms, there is no doubt that to enable further application in future it will be necessary to match such research with studies of oxygen transfer and energy supply to high viscosity fluids. Hence, the implementation of innovative solutions (some of which in principle are already possible) will be essential to ensure the further development of such fermentations.
Original languageEnglish
Title of host publicationIndustrial Scale Suspension Culture of Living Cells
EditorsHans-Peter Meyer, Diego R. Schmidhalter
Publication date2014
ISBN (Print)978-3-527-33547-3
Publication statusPublished - 2014


  • Fermenter design
  • Fermenter operation
  • Filamentous fungi
  • Industrial fermentation

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