Field programmable gate array-based real-time optical Doppler tomography system for in vivo imaging of cardiac dynamics in the chick embryo

Lars Thrane, Henning Engelbrecht Larsen, Kambiz Norozi, Finn Pedersen, Jakob Borup Thomsen, Maja Trojer, Talât Mesud Yelbuz

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

We demonstrate a field programmable gate-array-based real-time optical Doppler tomography system. A complex-valued bandpass filter is used for the first time in optical coherence tomography signal processing to create the analytic signal. This method simplifies the filter design, and allows efficient and compact implementation by combining the conversion to an analytic signal with a pulse shaping function without the need for extra resources as compared to the Hilbert transform method. The conversion of the analytic signal to amplitude and phase is done by use of the coordinate rotation digital computer (CORDIC) algorithm, which is an efficient algorithm that maps well to the field programmable gate array. Flow phantom experiments, and the use of this system for in vivo imaging of cardiac dynamics in the chick embryo, are presented. We demonstrate the visualization of blood flow in the early embryonic heart as well as in the aorta, small peripheric vitelline vessels, and coronary arteries of fully formed chick hearts. (c) 2009 Society of Photo-Optical Instrumentation Engineers.
Original languageEnglish
JournalOptical Engineering
Volume48
Issue number2
Pages (from-to)023201
ISSN0091-3286
DOIs
Publication statusPublished - 2009

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