Field observations on the duration of immunity in cattle after vaccination against Anaplasma and Babesia species

Kirsten Tjørnehøj, J. A. Lawrence, A. P. Whiteland, P. T. Kafuwa

Research output: Contribution to journalJournal articleResearchpeer-review


In an outbreak of Babesia bovis in a large herd of Friesian x Malawi Zebu cattle, which occurred after an interruption of intensive dipping, clinical or fatal babesiosis occurred in 54/299 (18,1%) animals which had never been vaccinated, as compared to 9/153 (5,9%) vaccinated animals. Eight of the nine affected vaccinates had been vaccinated more than 27 months previously.Sera were collected every 3-4 months from 33 Friesian x Malawi Zebu heifers maintained with intensive dipping and vaccinated with trivalent B. bovis, Babesia bigemina and Anaplasma centrale vaccine. After 2 years, 25% had become seronegative for B. bovis by indirect immunofluorescence, as compared to 97% for B. bigemina and 46% for A. centrale.Because of the evidence that immunity following vaccination against B. bovis declines after 2 years in the absence of tick challenge, it is recommended that tick control should be relaxed after immunity has been established, in order to save acaricide, reinforce immunity and avoid any need for revaccination.
Original languageEnglish
JournalOnderstepoort Journal of Veterinary Research
Issue number1
Pages (from-to)1-5
Number of pages5
Publication statusPublished - 1996
Externally publishedYes


  • Veterinary (all)
  • Life Sciences
  • Anaplasma
  • Babesia
  • Cattle
  • Duration
  • Immunity
  • Vaccination
  • protozoon antibody
  • active immunization
  • anaplasmosis
  • animal
  • article
  • babesiosis
  • blood
  • cattle
  • cattle disease
  • immunology
  • vaccination
  • Anaplasmosis
  • Animals
  • Antibodies, Protozoan
  • Babesiosis
  • Cattle Diseases
  • Immunity, Active
  • duration
  • immunity


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