Abstract
Feasibility of bovine submaxillary mucin (BSM) films generated via spontaneous adsorption from aqueous solutions onto polydimethylsiloxane (PDMS) and polystyrene (PS) surfaces have been investigated as biomimetic coatings for polymeric biomaterials. Two attributes as biomedical coatings, namely anti-fouling properties and lubricity, have been focused on in this study. Optical waveguide light-mode spectroscopy (OWLS) and fluorescence microscopy studies have shown that albumin, fibrinogen, immunoglobulin G, and serum rapidly adsorb onto BSM layers formed on PDMS and PS surfaces. Pin-on-disk tribometry, employing compliant PDMS as tribopairs, has shown that BSM coatings generated on PDMS surface via spontaneous adsorption from aqueous solution has effective lubricating properties, but for very limited duration only.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the IASTED International Conference on Biomedical Engineering, BioMed 2013 |
| Number of pages | 7 |
| Publication date | 2013 |
| Pages | 591-597 |
| DOIs | |
| Publication status | Published - 2013 |
| Event | The 10th IASTED International Conference on Biomedical Engineering - Innsbruck, Austria Duration: 13 Feb 2013 → 15 Feb 2013 Conference number: 10 |
Conference
| Conference | The 10th IASTED International Conference on Biomedical Engineering |
|---|---|
| Number | 10 |
| Country | Austria |
| City | Innsbruck |
| Period | 13/02/2013 → 15/02/2013 |
Keywords
- Biofouling
- Biomedical coating
- Bovine submaxillary mucin (BSM)
- Lubricity