Feasibility of bovine submaxillary mucin (BSM) films as biomimetic coating for polymeric biomaterials

Seunghwan Lee, Jan Busk Madsen, Kirsi I. Pakkanen

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    Feasibility of bovine submaxillary mucin (BSM) films generated via spontaneous adsorption from aqueous solutions onto polydimethylsiloxane (PDMS) and polystyrene (PS) surfaces have been investigated as biomimetic coatings for polymeric biomaterials. Two attributes as biomedical coatings, namely anti-fouling properties and lubricity, have been focused on in this study. Optical waveguide light-mode spectroscopy (OWLS) and fluorescence microscopy studies have shown that albumin, fibrinogen, immunoglobulin G, and serum rapidly adsorb onto BSM layers formed on PDMS and PS surfaces. Pin-on-disk tribometry, employing compliant PDMS as tribopairs, has shown that BSM coatings generated on PDMS surface via spontaneous adsorption from aqueous solution has effective lubricating properties, but for very limited duration only.
    Original languageEnglish
    Title of host publicationProceedings of the IASTED International Conference on Biomedical Engineering, BioMed 2013
    Number of pages7
    Publication date2013
    Pages591-597
    DOIs
    Publication statusPublished - 2013
    EventThe 10th IASTED International Conference on Biomedical Engineering - Innsbruck, Austria
    Duration: 13 Feb 201315 Feb 2013
    Conference number: 10

    Conference

    ConferenceThe 10th IASTED International Conference on Biomedical Engineering
    Number10
    Country/TerritoryAustria
    CityInnsbruck
    Period13/02/201315/02/2013

    Keywords

    • Biofouling
    • Biomedical coating
    • Bovine submaxillary mucin (BSM)
    • Lubricity

    Fingerprint

    Dive into the research topics of 'Feasibility of bovine submaxillary mucin (BSM) films as biomimetic coating for polymeric biomaterials'. Together they form a unique fingerprint.

    Cite this