Fast differential scanning calorimetry of liquid samples with chips

R. Splinter, A. W. van Herwaarden, I. A. van Wetten, Andrea Pfreundt, Winnie Edith Svendsen

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Based on a modified version of standard chips for fast differential scanning calorimetry, DSC of liquid samples has been performed at temperature scan rates of up to 1000 °C/s. This paper describes experimental results with the protein lysozyme, bovine serum, and olive oil. The heating and cooling rate of the sensor is measured for temperature scan rates of up to 1300 °C/s with water and 2-butanol, in the temperature range of −90 °C/s to +130 °C/s. The lysozyme is measured at temperature scan rates varying from 10 °C/s to 400 °C/s and in concentrations between 0.1% and 10% protein by weight. The bovine serum measurements show two main peaks, in good agreement with standard DSC measurements. Olive oil has been measured, with good agreement for the cooling curve and qualitative agreement for the heater curve, compared to DSC measurements.
    Original languageEnglish
    JournalThermochimica Acta
    Volume603
    Pages (from-to)162–171
    Number of pages10
    ISSN0040-6031
    DOIs
    Publication statusPublished - 2015

    Keywords

    • Liquid calorimetry
    • Fast DSC
    • Serum DSC
    • Olive oil DSC

    Cite this

    Splinter, R., van Herwaarden, A. W., van Wetten, I. A., Pfreundt, A., & Svendsen, W. E. (2015). Fast differential scanning calorimetry of liquid samples with chips. Thermochimica Acta, 603, 162–171. https://doi.org/10.1016/j.tca.2014.07.013