FARO server: Meta-analysis of gene expression by matching gene expression signatures to a compendium of public gene expression data

Mieszko P. Manijak, Henrik Bjørn Nielsen

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    Abstract

    BACKGROUND: Although, systematic analysis of gene annotation is a powerful tool for interpreting gene expression data, it sometimes is blurred by incomplete gene annotation, missing expression response of key genes and secondary gene expression responses. These shortcomings may be partially circumvented by instead matching gene expression signatures to signatures of other experiments. FINDINGS: To facilitate this we present the Functional Association Response by Overlap (FARO) server, that match input signatures to a compendium of 242 gene expression signatures, extracted from more than 1700 Arabidopsis microarray experiments. CONCLUSIONS: Hereby we present a publicly available tool for robust characterization of Arabidopsis gene expression experiments which can point to similar experimental factors in other experiments. The server is available at http://www.cbs.dtu.dk/services/faro/.
    Original languageEnglish
    JournalBMC Research Notes
    Volume4
    Issue number1
    Pages (from-to)181
    ISSN1756-0500
    DOIs
    Publication statusPublished - 2011

    Bibliographical note

    © 2011 Nielsen et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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