Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study

Sarah L. Lambton; Adrian D. Colloff; Richard P. Smith; George L. Caldow; Sandra F. E. Scholes; Kim Willoughby; Fiona Howie; Johanne Ellis-Iversen; Graham David; Alasdair J. C. Cook; Andrew Holliman; Simon Gubbins

doi:10.1371/journal.pone.0034183

Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study

Sarah L. Lambton, Adrian D. Colloff, Richard P. Smith, George L. Caldow, Sandra F. E. Scholes, Kim Willoughby, Fiona Howie, Johanne Ellis-Iversen, Graham David, Alasdair J. C. Cook, Andrew Holliman, Simon Gubbins (Editor)

Research output: Contribution to journal › Journal article › Research › peer-review

48 Downloads (Pure)

Abstract

Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries during recent years. Data were retrospectively collected during June to November 2010 for 56 case calves diagnosed with BNP between 17 March and 7 June of the same year. These were compared with 58 control calves randomly recruited from herds with no history of BNP. Multivariable logistic regression analysis showed that increased odds of a calf being a BNP case were associated with its dam having received PregSure® BVD (Pfizer Animal Health) vaccination prior to the birth of the calf (odds ratio (OR) 40.78, p

Original language	English
Journal	P L o S One
Volume	7
Issue number	5
Pages (from-to)	e34183
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0034183
Publication status	Published - 2012
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1371/journal.pone.0034183

JournalFinal published version, 119 KB

OpenUrl availability

Full text

Cite this

@article{e3d6059aa7c7432c95b1a041850075f6,

title = "Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study",

abstract = "Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries during recent years. Data were retrospectively collected during June to November 2010 for 56 case calves diagnosed with BNP between 17 March and 7 June of the same year. These were compared with 58 control calves randomly recruited from herds with no history of BNP. Multivariable logistic regression analysis showed that increased odds of a calf being a BNP case were associated with its dam having received PregSure{\textregistered} BVD (Pfizer Animal Health) vaccination prior to the birth of the calf (odds ratio (OR) 40.78, p",

author = "Lambton, {Sarah L.} and Colloff, {Adrian D.} and Smith, {Richard P.} and Caldow, {George L.} and Scholes, {Sandra F. E.} and Kim Willoughby and Fiona Howie and Johanne Ellis-Iversen and Graham David and Cook, {Alasdair J. C.} and Andrew Holliman and Simon Gubbins",

year = "2012",

doi = "10.1371/journal.pone.0034183",

language = "English",

volume = "7",

pages = "e34183",

journal = "P L o S One",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "5",

}

TY - JOUR

T1 - Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves

T2 - A Case-Control Study

AU - Lambton, Sarah L.

AU - Colloff, Adrian D.

AU - Smith, Richard P.

AU - Caldow, George L.

AU - Scholes, Sandra F. E.

AU - Willoughby, Kim

AU - Howie, Fiona

AU - Ellis-Iversen, Johanne

AU - David, Graham

AU - Cook, Alasdair J. C.

AU - Holliman, Andrew

A2 - Gubbins, Simon

PY - 2012

Y1 - 2012

N2 - Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries during recent years. Data were retrospectively collected during June to November 2010 for 56 case calves diagnosed with BNP between 17 March and 7 June of the same year. These were compared with 58 control calves randomly recruited from herds with no history of BNP. Multivariable logistic regression analysis showed that increased odds of a calf being a BNP case were associated with its dam having received PregSure® BVD (Pfizer Animal Health) vaccination prior to the birth of the calf (odds ratio (OR) 40.78, p

AB - Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries during recent years. Data were retrospectively collected during June to November 2010 for 56 case calves diagnosed with BNP between 17 March and 7 June of the same year. These were compared with 58 control calves randomly recruited from herds with no history of BNP. Multivariable logistic regression analysis showed that increased odds of a calf being a BNP case were associated with its dam having received PregSure® BVD (Pfizer Animal Health) vaccination prior to the birth of the calf (odds ratio (OR) 40.78, p

U2 - 10.1371/journal.pone.0034183

DO - 10.1371/journal.pone.0034183

M3 - Journal article

SN - 1932-6203

VL - 7

SP - e34183

JO - P L o S One

JF - P L o S One

IS - 5

ER -

Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study

Abstract

UN SDGs

Access to Document

OpenUrl availability

Fingerprint

Cite this