Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study

Sarah L. Lambton, Adrian D. Colloff, Richard P. Smith, George L. Caldow, Sandra F. E. Scholes, Kim Willoughby, Fiona Howie, Johanne Ellis-Iversen, Graham David, Alasdair J. C. Cook, Andrew Holliman, Simon Gubbins (Editor)

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Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries during recent years. Data were retrospectively collected during June to November 2010 for 56 case calves diagnosed with BNP between 17 March and 7 June of the same year. These were compared with 58 control calves randomly recruited from herds with no history of BNP. Multivariable logistic regression analysis showed that increased odds of a calf being a BNP case were associated with its dam having received PregSure® BVD (Pfizer Animal Health) vaccination prior to the birth of the calf (odds ratio (OR) 40.78, p
Original languageEnglish
JournalP L o S One
Issue number5
Pages (from-to)e34183
Publication statusPublished - 2012
Externally publishedYes


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