Fabrication of Three Dimensional Tissue Engineering Polydimethylsiloxane ( PDMS) Microporous Scaffolds Integrated in a Bioreactor Using a 3D Printed Water Dissolvable Sacrificial Mould

Soumyaranjan Mohanty, Ioannis Mantis, Aradhya Mallikarjunaiah Chetan, Layla Bashir Larsen, Martin Dufva, Jenny Emnéus, Anders Wolff

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    We present a new scalable and general approach for manufacturing structured pores/channels in 3D polymer based scaffolds. The method involves 3D printing of a sacrificial polyvinyl alcohol (PVA) mould whose geometrical features are designed according to the required vascular channel network. Polydimethylsiloxane (PDMS) polymer is cast around the PVA mould, cross-linked and then the mould is dissolved, leaving behind a structured porous PDMS scaffold. The fabrication method described here is demonstrated with silicone elastomer but various other natural and synthetic polymers are compatible with this fabrication technique
    Original languageEnglish
    Title of host publicationProceedings MicroTAS 2015
    Publication date2015
    Pages1439-1441
    Publication statusPublished - 2015
    EventMicroTAS 2015: 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Gyeongju, Korea, Republic of
    Duration: 25 Oct 201529 Oct 2015
    Conference number: 19

    Conference

    ConferenceMicroTAS 2015
    Number19
    CountryKorea, Republic of
    CityGyeongju
    Period25/10/201529/10/2015

    Fingerprint Dive into the research topics of 'Fabrication of Three Dimensional Tissue Engineering Polydimethylsiloxane ( PDMS) Microporous Scaffolds Integrated in a Bioreactor Using a 3D Printed Water Dissolvable Sacrificial Mould'. Together they form a unique fingerprint.

    Cite this