Fabrication and loading of oral drug delivery microcontainers using hot punching

Ritika Singh Petersen, Mads T. Borre, Stephan Sylvest Keller, Anja Boisen

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

In this paper, poly-l-lactic acid (PLLA) solution is spin coated to achieve a PLLA layer of 55 μm thickness. Hot punching with a Ni stamp is optimized to fabricate microcontainers in PLLA. Process optimization of thermal bonding of the microcontainers to a poly acrylic acid (PAA) layer is performed by modifying sample preparation and varying temperature. The fabricated microcontainers are loaded by hot punching in a spin coated drug polymer film of furosemide and poly-e-caprolactone (PCL).
Original languageEnglish
Title of host publication19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Number of pages3
PublisherChemical and Biological Microsystems Society
Publication date2015
Pages844-846
ISBN (Print)9780979806483
Publication statusPublished - 2015
EventMicroTAS 2015: 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Gyeongju, Korea, Republic of
Duration: 25 Oct 201529 Oct 2015
Conference number: 19

Conference

ConferenceMicroTAS 2015
Number19
Country/TerritoryKorea, Republic of
CityGyeongju
Period25/10/201529/10/2015

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