Fabrication and Characterization of 3D Micro- and Nanoelectrodes for Neuron Recordings

Maria Dimaki, Patricia Vazquez, Mark Holm Olsen, Luigi Sasso, Romén Rodriguez-Trujíllo, Indumathi Vedarethinam, Winnie Edith Svendsen

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    Abstract

    In this paper we discuss the fabrication and characterization of three dimensional (3D) micro- and nanoelectrodes with the goal of using them for extra- and intracellular studies. Two different types of electrodes will be described: high aspect ratio microelectrodes for studying the communication between cells and ultimately for brain slice recordings and small nanoelectrodes for highly localized measurements and ultimately for intracellular studies. Electrical and electrochemical characterization of these electrodes as well as the results of PC12 cell differentiation on chip will be presented and discussed.
    Original languageEnglish
    JournalSensors
    Volume10
    Issue number11
    Pages (from-to)10339-10355
    ISSN1424-8220
    DOIs
    Publication statusPublished - 2010

    Bibliographical note

    This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

    Keywords

    • fabrication
    • neuron differentiation on chip
    • 3D electrodes

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