TY - CHAP
T1 - Extracts from the Liverwort Bazzania trilobata with Potential Dermo-cosmetic Properties
AU - Marques, Raíssa Volpatto
AU - Salwinski, Aleksander
AU - Enemark-Rasmussen, Kasper
AU - Gotfredsen, Charlotte H.
AU - Lu, Yi
AU - Hocquigny, Nicolas
AU - Risler, Arnaud
AU - Duval, Raphaël E.
AU - Miguel, Sissi
AU - Bourgaud, Frédéric
AU - Simonsen, Henrik Toft
PY - 2023
Y1 - 2023
N2 - Bazzania trilobata (L.) Gray is a leafy liverwort from the family of Lepidoziaceae, well known for its antifungal properties. In this study, the 70% ethanol and methanol extracts of B. trilobata were investigated for new in vitro biological activities of cosmetic interest. The results showed that the total phenol content, the DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging activity, and the anti-collagenase activity of the 70% ethanol extract were higher than for methanol. The methanol extract showed mild tyrosinase inhibitory activity and antimicrobial properties towards the Gram-positive bacteria Enterococcus faecalis. Lignans, coumarins, and bis-bibenzyls were the major classes of phenolic constituents tentatively identified in both extracts. In addition, a known drimenyl caffeate was identified in B. trilobata and its structure was confirmed by NMR spectroscopy. These results suggest that extracts from B. trilobata could be exploited as an interesting new source of natural active ingredients for cosmetic applications.
AB - Bazzania trilobata (L.) Gray is a leafy liverwort from the family of Lepidoziaceae, well known for its antifungal properties. In this study, the 70% ethanol and methanol extracts of B. trilobata were investigated for new in vitro biological activities of cosmetic interest. The results showed that the total phenol content, the DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging activity, and the anti-collagenase activity of the 70% ethanol extract were higher than for methanol. The methanol extract showed mild tyrosinase inhibitory activity and antimicrobial properties towards the Gram-positive bacteria Enterococcus faecalis. Lignans, coumarins, and bis-bibenzyls were the major classes of phenolic constituents tentatively identified in both extracts. In addition, a known drimenyl caffeate was identified in B. trilobata and its structure was confirmed by NMR spectroscopy. These results suggest that extracts from B. trilobata could be exploited as an interesting new source of natural active ingredients for cosmetic applications.
KW - Antioxidant
KW - Antimicrobial
KW - Bazzania trilobata
KW - Collagenase inhibitory activity
KW - Drimenyl caffeate
KW - Tyrosinase inhibitory activity
U2 - 10.1007/978-3-031-23243-5_9
DO - 10.1007/978-3-031-23243-5_9
M3 - Book chapter
SN - 978-3-031-23242-8
VL - 683
T3 - Reference Series in Phytochemistry
SP - 147
EP - 164
BT - Bioactive Compounds in Bryophytes and Pteridophytes
A2 - Murthy, Hosakatte Niranjana
PB - Springer
ER -