Expression and functional studies of genes involved in transport and metabolism of glycerol in Pachysolen tannophilus.

Xiaoying Liu, Uffe Hasbro Mortensen, Mhairi Workman

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    Abstract

    P. tannophilus has characteristics relevant for a microbial cell factory to be applied in a biorefinery setting, i.e. its ability to utilise the carbon sources such as xylose and glycerol. However, the strain is not currently amenable to genetic modification and transformation. Heterologous expression of the glycerol transporters from P. tannophilus, which has a relatively high growth rate on glycerol, could be used as an approach for improving the efficiency of glycerol assimilation in other well characterized and applied cell factories such as S. cerevisiae.
    Original languageEnglish
    JournalMicrobial Cell Factories
    Volume12
    Pages (from-to)27
    ISSN1475-2859
    Publication statusPublished - 2013

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