Experimental in utero infection of pig foetuses with porcine parvovirus (PPV)

Jens Nielsen, L. Rønsholt, K. J. Sørensen

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Pig foetuses of various gestational ages were exposed to experimental infection with porcine parvavirus (PPV) in utero. Inoculation of 40-, 50- and 60-day-old foetuses with PPV caused foetal death and mummification and spread of the infection to non-inoculated foetuses. Inoculation at 80 and 100 days gestation caused pathological lesions of various degrees whereas spread of infection occurred only sporadically. Serological examinations of foetuses of different ages suggest that immunocompetence for PPV develops before 70 days gestation. The present results strongly indicate that intrauterine spread of PPV is a route of transmission of this virus between pig foetuses.
    Original languageEnglish
    JournalVeterinary Microbiology
    Volume28
    Issue number1
    Pages (from-to)1-11
    ISSN0378-1135
    DOIs
    Publication statusPublished - 1991

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