Abstract
| Original language | English |
|---|---|
| Journal | Journal of Pathogens |
| Volume | 2013 |
| Pages (from-to) | 534342 |
| Number of pages | 7 |
| ISSN | 2090-3065 |
| DOIs | |
| Publication status | Published - 2013 |
Bibliographical note
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Cite this
}
Experimental Airborne Transmission of Porcine Postweaning Multisystemic Wasting Syndrome. / Kristensen, C. S.; Hjulsager, Charlotte Kristiane; Vestergaard, K.; Dupont, Kitt; Bille-Hansen, Vivi; Enøe, Claes; Jorsal, Sven Erik Lind; Bækbo, P.; Larsen, Lars Erik.
In: Journal of Pathogens, Vol. 2013, 2013, p. 534342.Research output: Contribution to journal › Journal article › Research › peer-review
TY - JOUR
T1 - Experimental Airborne Transmission of Porcine Postweaning Multisystemic Wasting Syndrome
AU - Kristensen, C. S.
AU - Hjulsager, Charlotte Kristiane
AU - Vestergaard, K.
AU - Dupont, Kitt
AU - Bille-Hansen, Vivi
AU - Enøe, Claes
AU - Jorsal, Sven Erik Lind
AU - Bækbo, P.
AU - Larsen, Lars Erik
N1 - This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
PY - 2013
Y1 - 2013
N2 - The objective of these studies was to investigate if porcine postweaning multisystemic wasting syndrome (PMWS) could be induced in healthy pigs following contact with air from pigs with clinical signs of PMWS. The pigs were housed in different units. Either 31 (study I) or 25 (study II) pigs with clinical symptoms of PMWS from a PMWS-affected herd and 25 healthy pigs from a PMWS-free, but PCV2-positive, herd were housed in unit A. Fifty pigs from a PMWS-free herd were housed in unit B, which were connected by pipes to unit A. In unit C, 30 pigs from a PMWS-free herd were housed as controls. In study II, the pigs in units A and B from the PMWS-free herd developed clinical signs of PMWS 2-3 weeks after arrival. PMWS was confirmed at necropsy and the diseased pigs had increased PCV2 load and increased antibody titers against PCV2 in serum that coincided with the development of clinical signs typical of PMWS. Sequence analysis revealed that the PCV2 isolate belonged to genotype 2b. In conclusion, the present study showed that PMWS can be induced in pigs from a PMWS-free herd by airborne contact with pigs from a PMWS-affected herd.
AB - The objective of these studies was to investigate if porcine postweaning multisystemic wasting syndrome (PMWS) could be induced in healthy pigs following contact with air from pigs with clinical signs of PMWS. The pigs were housed in different units. Either 31 (study I) or 25 (study II) pigs with clinical symptoms of PMWS from a PMWS-affected herd and 25 healthy pigs from a PMWS-free, but PCV2-positive, herd were housed in unit A. Fifty pigs from a PMWS-free herd were housed in unit B, which were connected by pipes to unit A. In unit C, 30 pigs from a PMWS-free herd were housed as controls. In study II, the pigs in units A and B from the PMWS-free herd developed clinical signs of PMWS 2-3 weeks after arrival. PMWS was confirmed at necropsy and the diseased pigs had increased PCV2 load and increased antibody titers against PCV2 in serum that coincided with the development of clinical signs typical of PMWS. Sequence analysis revealed that the PCV2 isolate belonged to genotype 2b. In conclusion, the present study showed that PMWS can be induced in pigs from a PMWS-free herd by airborne contact with pigs from a PMWS-affected herd.
U2 - 10.1155/2013/534342
DO - 10.1155/2013/534342
M3 - Journal article
VL - 2013
SP - 534342
JO - Journal of Pathogens
JF - Journal of Pathogens
SN - 2090-3065
ER -