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Expediting pathogen genomics adoption for enhanced foodborne disease surveillance in Africa

  • Aquillah M. Kanzi*
  • , Stella I. Smith
  • , Chisomo Msefula
  • , John Mwaba
  • , Abraham Ajayi
  • , Geoffrey Kwenda
  • , Collins K. Tanui
  • , Anthony M. Smith
  • , Linda A. Bester
  • , Firehiwot A. Derra
  • , Kaunda Yamba
  • , Daniel L. Banda
  • , John B. Kalule
  • , Happiness H. Kumburu
  • , Yasmina J. Fakim
  • , Nyasha Sithole
  • , Patrick M.K. Njage
  • , Francis F. Chikuse*
  • , Pascale Ondoa
  • , Sofonias K. Tessema
  • Ebenezer Foster-Nyarko
*Corresponding author for this work
  • University of KwaZulu-Natal
  • Nigerian Institute of Medical Research
  • Kamuzu University of Health Sciences
  • Levy Mwanawasa Medical University
  • University of Zambia
  • Africa Centres for Disease Control and Prevention
  • University of Pretoria
  • University of Venda
  • Ethiopia Public Health Institute
  • Zambia National Public Health Institute
  • Makerere University
  • Kilimanjaro Christian Medical College
  • University of Mauritius
  • African Society for Laboratory Medicine
  • London School of Hygiene and Tropical Medicine

Research output: Contribution to journalReviewpeer-review

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Abstract

The role of genomics in public health surveillance has been accentuated by its crucial contributions during the COVID-19 pandemic, demonstrating its potential in addressing global disease outbreaks. While Africa has made strides in expanding multi-pathogen genomic surveillance, the integration into foodborne disease (FBD) surveillance remains nascent. Here we highlight the critical components to strengthen and scale-up the integration of whole genome sequencing (WGS) in foodborne disease surveillance across the continent. We discuss priority use-cases for FBD, and strategies for the implementation. We also highlight the major challenges such as data management, policy and regulatory frameworks, stakeholder engagement, the need for multidisciplinary collaborations and the importance of robust monitoring and evaluation, aiming to bolster Africa's preparedness and response to future health threats.

Original languageEnglish
Article number105500
JournalEBioMedicine
Volume111
Number of pages9
ISSN2352-3964
DOIs
Publication statusPublished - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Food-borne diseases
  • Pathogen genomics
  • Genomic surveillance
  • Public health
  • Whole-genome sequencing
  • Africa

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