Leaving marks: The number of known posttranslational modifications for lysine has been expanded considerably. In addition to acetylation of side-chain amino functionalities of lysine residues in proteins, crotonylation, succinylation, and malonylation have now been identified as posttranslational modifications in histone and in non-histone proteins.
Bibliographical noteFinancial support from the Lundbeck Foundation (Young Group Leader Fellowship) and the Danish Independent Research Council – Natural Sciences (Steno Grant No. 10-080907) is gratefully acknowledged.
- Protein modifications