Expanding the species and chemical diversity of Penicillium section Cinnamopurpurea

Stephen W. Peterson, Željko Jurjević, Jens Christian Frisvad

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    Abstract

    A set of isolates very similar to or potentially conspecific with an unidentified Penicillium isolate NRRL 735, was assembled using a BLAST search of ITS similarity among described (GenBank) and undescribed Penicillium isolates in our laboratories. DNA was amplified from six loci of the assembled isolates and sequenced. Two species in section Cinnamopurpurea are self-compatible sexual species, but the asexual species had polymorphic loci suggestive of sexual reproduction and variation in conidium size suggestive of ploidy level differences typical of heterothallism. Accordingly we use genealogical concordance analysis, a technique valid only in heterothallic organisms, for putatively asexual species. Seven new species were revealed in the analysis and are described here. Extrolite analysis showed that two of the new species, P. colei and P. monsserratidens produce the mycotoxin citreoviridin that has demonstrated pharmacological activity against human lung tumors. These isolates could provide leads in pharmaceutical research.
    Original languageEnglish
    Article numbere0121987
    JournalP L o S One
    Volume10
    Issue number4
    Number of pages28
    ISSN1932-6203
    DOIs
    Publication statusPublished - 2015

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