Examination of virus shedding in semen from vaccinated and from previously infected boars after experimental challenge with porcine reproductive and respiratory syndrome virus

Thomas L. Nielsen, Jens Nielsen, Per Have, P. Baekbo, R. Hoff-Jørgensen, Anette Bøtner

    Research output: Contribution to journalJournal articlepeer-review

    Abstract

    Danish artificial insemination (AI) centres house several boars antibody positive to porcine reproductive and respiratory syndrome virus as well as PRRSV-naive boars which may become acutely infected, The risk of transmission of PRRSV by semen may therefore constitute a serious problem to the Danish pig industry. The use of a vaccination-program may be a way to avoid or reduce the problem, This study evaluates the use of two vaccines: One live, attenuated vaccine and one inactivated vaccine, A pronounced reduction in viremia and shedding of virus in semen was demonstrated by use of the live vaccine compared to the non-vaccinated control animals. In contrast, no changes in onset, level and duration of viremia and shedding of virus in semen were observed using the inactivated vaccine, Neither viremia nor seminal shedding of virus was detected in previously PRRSV-infected, PRRSV-antibody positive boars after challenge with a Danish field strain of PRRSV.
    Original languageEnglish
    JournalVeterinary Microbiology
    Volume54
    Issue number2
    Pages (from-to)101-112
    ISSN0378-1135
    DOIs
    Publication statusPublished - 1997

    Keywords

    • porcine reproductive and respiratory syndrome
    • pig-viruses
    • artificial insemination
    • vaccine

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