Estimating and suppressing background in Raman spectra with an artificial neural network

Sigurdur Sigurdsson, Jan Larsen, Peter Alshede Philipsen, Monika Gniadecka, Hans Christian Wulf, Lars Kai Hansen

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    Abstract

    In this report we address the problem of skin fluorescence in feature extraction from Raman spectra of skin lesions. We apply a highly automated neural network method for suppressing skin fluorescence from Raman spectrum of skin lesions before dimension reduction with principal components analysis. By applying the background suppression, the effect of outlier spectrum in the principal components analysis was greatly reduced.
    Original languageEnglish
    Publication statusPublished - 2003

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