Enzymatic Modification of Sphingomyelin

Long Zhang, Lars Hellgren, Xuebing Xu

    Research output: Contribution to conferencePosterResearch


    Due to its major role in maintaining the water-retaining properties of the epidermis, ceramide is of great commercial potential in cosmetic and pharmaceuticals such as hair and skin care products. Currently, chemical synthesis of ceramide is a costly process, and developments of alternative cost-efficient, high yield production methods are of great interest. In the present study, the potential of producing ceramide through enzymatic hydrolysis of sphingomyelin have been studied. Sphingomyelin (SM) is a ubiquitous membrane-lipid and dairy products or by-products is a rich source of sphingomyelin. In present study, we have optimized the production of ceramide from sphingomyelin using Phospholipase C from Clostridium perfringens.
    Original languageEnglish
    Publication date2005
    Publication statusPublished - 2005
    Event12th European Congress on Biotechnology - Kongens Lyngby, Denmark
    Duration: 21 Aug 200524 Aug 2005
    Conference number: 12


    Conference12th European Congress on Biotechnology
    CityKongens Lyngby


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