Entrapment of Radionuclides in Nanoparticle Compositions

Thomas Lars Andresen (Inventor), Anncatrine Luisa Petersen (Inventor), Jonas Rosager Henriksen (Inventor), Palle Rasmussen (Inventor), Andreas kjær (Inventor)

Research output: Patent

Abstract

The present invention is directed to the technical field of imaging compositions useful for diagnosing cancer and other diseases in a subject. In particular, the invention relates to a class of diagnostic compounds comprising a novel liposome composition with encapsulated metal entities such as radionuclides,for example 61Cu and 64Cu copper isotopes. The invention further relates to a novel method for loading delivery systems, such as liposome compositions, with metal entities such as radionuclides, and the use of liposomes for targeted diagnosis and treatment of a target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique.
Original languageEnglish
IPCA61K47/28
Patent numberWO2012079582
Filing date21/06/2012
CountryDenmark
Publication statusPublished - 2012

Bibliographical note

DTU reference nummer: 92555-10

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