Abstract
The human gut microbiota plays an important role for the health of the host. The question is whether we can modulate the gut microbiota by changing diet. During a 6-month, randomised, controlled dietary intervention, the effect of a moderate diet shift from Average Danish Diet to New Nordic Diet on the gut microbiota in humans (n=62) was investigated. Quantitative PCR analysis showed that the microbiota did not change significantly by the intervention.
Nevertheless, by stratifying subjects into two enterotypes, distinguished by the Prevotella/Bacteroides ratio (P/B), we were able to detect significant changes in the gut microbiota composition resulting from the interventions. Subjects with a high-P/B experienced more pronounced changes in the gut microbiota composition than subjects with a low-P/B. The study is the first to indicate that enterotypes influence microbiota response to a dietary intervention.
Nevertheless, by stratifying subjects into two enterotypes, distinguished by the Prevotella/Bacteroides ratio (P/B), we were able to detect significant changes in the gut microbiota composition resulting from the interventions. Subjects with a high-P/B experienced more pronounced changes in the gut microbiota composition than subjects with a low-P/B. The study is the first to indicate that enterotypes influence microbiota response to a dietary intervention.
| Original language | English |
|---|---|
| Publication date | 2013 |
| Number of pages | 1 |
| Publication status | Published - 2013 |
| Event | Cell Symposia: Microbiome and Host Health - Lisbon, Portugal Duration: 12 May 2013 → 14 May 2013 http://www.cell-symposia-microbiome.com/ |
Conference
| Conference | Cell Symposia |
|---|---|
| Country/Territory | Portugal |
| City | Lisbon |
| Period | 12/05/2013 → 14/05/2013 |
| Internet address |
