Engineering synergy in biotechnology

Jens Nielsen, Martin Fussenegger, Jay Keasling, Sang Yup Lee, James C. Liao, Kristala Prather, Bernhard Palsson

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Abstract

In this article, the author focuses on approaches in metabolic engineering and synthetic biology for the creation of efficient cell factories, which can be bused to convert biomass and other feedstocks for the generation of chemicals. Topics discussed include development of restriction enzymes, engineering plasmids and recyclable markers, production of 1,3-propanediol using a metabolically engineered Escherichia coli and production of isobutanol by using metabolically engineered yeast.
Original languageEnglish
JournalNature Chemical Biology
Volume10
Issue number5
Pages (from-to)319-322
Number of pages4
ISSN1552-4450
DOIs
Publication statusPublished - 2014

Keywords

  • BIOCHEMISTRY
  • ESCHERICHIA-COLI
  • STRAIN IMPROVEMENT
  • SYNTHETIC BIOLOGY
  • CONSTRUCTION
  • PATHWAYS
  • GENOME
  • SWITCH
  • SYNTHETIC biology
  • Research

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