Engineered probiotic bacteria for prebiotic-responsive control of colonization

Kira Sarup-Lytzen; Marcia Søgaard Brinck; Felipe Senne de Oliveira Lino; Morten Otto Alexander Sommer; Mareike Bongers; Felipe Gonzalo Tueros Farfan

Engineered probiotic bacteria for prebiotic-responsive control of colonization

Kira Sarup-Lytzen (Inventor), Marcia Søgaard Brinck (Inventor), Felipe Senne de Oliveira Lino (Inventor), Morten Otto Alexander Sommer (Inventor), Mareike Bongers (Inventor), Felipe Gonzalo Tueros Farfan (Inventor)

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Abstract

The invention provides a recombinant probiotic gram-negative bacterium engineered to grow on a rare carbohydrate as sole carbon source, and whose ability to colonize the mammalian gut is responsive to the supply of said carbohydrate. The invention further provides a pharmaceutical composition or kit comprising the recombinant probiotic gram-negative bacterium and said carbohydrate.

Original language	English
IPC	C12P 21/ 02 A I
Patent number	WO2022013269
Filing date	15/07/2020
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	15/07/2020
Priority number	EP20200186080
Publication status	Published - 20 Jan 2022

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title = "Engineered probiotic bacteria for prebiotic-responsive control of colonization",

abstract = "The invention provides a recombinant probiotic gram-negative bacterium engineered to grow on a rare carbohydrate as sole carbon source, and whose ability to colonize the mammalian gut is responsive to the supply of said carbohydrate. The invention further provides a pharmaceutical composition or kit comprising the recombinant probiotic gram-negative bacterium and said carbohydrate.",

author = "Kira Sarup-Lytzen and Brinck, {Marcia S{\o}gaard} and Lino, {Felipe Senne de Oliveira} and Sommer, {Morten Otto Alexander} and Mareike Bongers and Farfan, {Felipe Gonzalo Tueros}",

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AU - Sarup-Lytzen, Kira

AU - Brinck, Marcia Søgaard

AU - Lino, Felipe Senne de Oliveira

AU - Sommer, Morten Otto Alexander

AU - Bongers, Mareike

AU - Farfan, Felipe Gonzalo Tueros

PY - 2022/1/20

Y1 - 2022/1/20

N2 - The invention provides a recombinant probiotic gram-negative bacterium engineered to grow on a rare carbohydrate as sole carbon source, and whose ability to colonize the mammalian gut is responsive to the supply of said carbohydrate. The invention further provides a pharmaceutical composition or kit comprising the recombinant probiotic gram-negative bacterium and said carbohydrate.

AB - The invention provides a recombinant probiotic gram-negative bacterium engineered to grow on a rare carbohydrate as sole carbon source, and whose ability to colonize the mammalian gut is responsive to the supply of said carbohydrate. The invention further provides a pharmaceutical composition or kit comprising the recombinant probiotic gram-negative bacterium and said carbohydrate.

M3 - Patent

M1 - WO2022013269

Y2 - 2020/07/15

ER -

Engineered probiotic bacteria for prebiotic-responsive control of colonization

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