Engineered probiotic bacteria for prebiotic-responsive control of colonization

Kira Sarup-Lytzen (Inventor), Marcia Søgaard Brinck (Inventor), Felipe Senne de Oliveira Lino (Inventor), Morten Otto Alexander Sommer (Inventor), Mareike Bongers (Inventor), Felipe Gonzalo Tueros Farfan (Inventor)

Research output: Patent

28 Downloads (Pure)

Abstract

The invention provides a recombinant probiotic gram-negative bacterium engineered to grow on a rare carbohydrate as sole carbon source, and whose ability to colonize the mammalian gut is responsive to the supply of said carbohydrate. The invention further provides a pharmaceutical composition or kit comprising the recombinant probiotic gram-negative bacterium and said carbohydrate.

Original languageEnglish
IPCC12P 21/ 02 A I
Patent numberWO2022013269
Filing date15/07/2020
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date15/07/2020
Priority numberEP20200186080
Publication statusPublished - 20 Jan 2022

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