Abstract
The invention provides engineered bacteria that secretes cytokines, such as interleukin 2 (IL-2) cytokine, for use in cancer immunotherapy, pharmaceutical compositions comprising the engineered bacteria, methods for producing recombinant therapeutical polypeptides, and methods for using the engineered bacteria for therapeutic purposes.
| Original language | English |
|---|---|
| IPC | C12N 15/ 62 A I |
| Patent number | WO2023161371 |
| Filing date | 25/02/2022 |
| Country/Territory | International Bureau of the World Intellectual Property Organization (WIPO) |
| Priority date | 25/02/2022 |
| Priority number | EP20220158950 |
| Publication status | Published - 31 Aug 2023 |
