Herein, we report stoichiometric investigations embodying the first highly enantioselective aryl-aryl coupling facilitated by a gold complex. With up to 91% ee, this is the first demonstration of a transmetalation and C(sp2)-C(sp2) reductive elimination sequence with high enantioselectivity using a gold complex. The results offer a basis for development of enantioselective gold-catalyzed aryl-aryl coupling reactions.
Himmelstrup, J., Buendia, M. B., Sun, X-W., & Kramer, S. (2019). Enantioselective aryl-aryl coupling facilitated by chiral binuclear gold complexes. Chemical Communications, 55(86), 12988-12991. https://doi.org/10.1039/c9cc07175j