Enantioselective aryl-aryl coupling facilitated by chiral binuclear gold complexes

Jonas Himmelstrup, Mikkel Burggraaf Buendia, Xing-Wen Sun, Søren Kramer*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Herein, we report stoichiometric investigations embodying the first highly enantioselective aryl-aryl coupling facilitated by a gold complex. With up to 91% ee, this is the first demonstration of a transmetalation and C(sp2)-C(sp2) reductive elimination sequence with high enantioselectivity using a gold complex. The results offer a basis for development of enantioselective gold-catalyzed aryl-aryl coupling reactions.
Original languageEnglish
JournalChemical Communications
Volume55
Issue number86
Pages (from-to)12988-12991
Number of pages4
ISSN1359-7345
DOIs
Publication statusPublished - 2019

Cite this

@article{12d4d05af7a34b28b3bf908ea4dd9928,
title = "Enantioselective aryl-aryl coupling facilitated by chiral binuclear gold complexes",
abstract = "Herein, we report stoichiometric investigations embodying the first highly enantioselective aryl-aryl coupling facilitated by a gold complex. With up to 91{\%} ee, this is the first demonstration of a transmetalation and C(sp2)-C(sp2) reductive elimination sequence with high enantioselectivity using a gold complex. The results offer a basis for development of enantioselective gold-catalyzed aryl-aryl coupling reactions.",
author = "Jonas Himmelstrup and Buendia, {Mikkel Burggraaf} and Xing-Wen Sun and S{\o}ren Kramer",
year = "2019",
doi = "10.1039/c9cc07175j",
language = "English",
volume = "55",
pages = "12988--12991",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "86",

}

Enantioselective aryl-aryl coupling facilitated by chiral binuclear gold complexes. / Himmelstrup, Jonas; Buendia, Mikkel Burggraaf; Sun, Xing-Wen; Kramer, Søren.

In: Chemical Communications, Vol. 55, No. 86, 2019, p. 12988-12991.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Enantioselective aryl-aryl coupling facilitated by chiral binuclear gold complexes

AU - Himmelstrup, Jonas

AU - Buendia, Mikkel Burggraaf

AU - Sun, Xing-Wen

AU - Kramer, Søren

PY - 2019

Y1 - 2019

N2 - Herein, we report stoichiometric investigations embodying the first highly enantioselective aryl-aryl coupling facilitated by a gold complex. With up to 91% ee, this is the first demonstration of a transmetalation and C(sp2)-C(sp2) reductive elimination sequence with high enantioselectivity using a gold complex. The results offer a basis for development of enantioselective gold-catalyzed aryl-aryl coupling reactions.

AB - Herein, we report stoichiometric investigations embodying the first highly enantioselective aryl-aryl coupling facilitated by a gold complex. With up to 91% ee, this is the first demonstration of a transmetalation and C(sp2)-C(sp2) reductive elimination sequence with high enantioselectivity using a gold complex. The results offer a basis for development of enantioselective gold-catalyzed aryl-aryl coupling reactions.

U2 - 10.1039/c9cc07175j

DO - 10.1039/c9cc07175j

M3 - Journal article

C2 - 31603439

VL - 55

SP - 12988

EP - 12991

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 86

ER -