Emerging strategies in 3D printed tissue models for in vitro biomedical research

Christian J. Pless; Carmen Radeke; Selgin D. Cakal; Janko Kajtez; Francesco S. Pasqualini; Johan U. Lind

doi:10.1016/B978-0-323-85430-6.00007-8

Emerging strategies in 3D printed tissue models for in vitro biomedical research

Christian J. Pless, Carmen Radeke, Selgin D. Cakal, Janko Kajtez, Francesco S. Pasqualini, Johan U. Lind

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Abstract

3D bioprinting has the potential to provide a unified framework for the manufacturing of tissue models for biomedical research, including drug discovery, disease modeling, and regenerative medicine. However, it remains challenging to 3D print replicas of human tissues that have accurate cell types, cellular densities, extracellular matrix compositions, and that can be assayed in a minimally invasive manner for chronic studies. Here, we review how recent breakthroughs in stem cell biology, tissue engineering, and materials science have led to novel 3D printing strategies that have the potential to solve these challenges.

Original language	English
Title of host publication	Bioprinting : From Multidisciplinary Design to Emerging Opportunities
Publisher	Elsevier
Publication date	2022
Pages	207-246
Chapter	7
ISBN (Print)	978-0-323-85431-3
ISBN (Electronic)	978-0-323-85430-6
DOIs	https://doi.org/10.1016/B978-0-323-85430-6.00007-8
Publication status	Published - 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-323-85430-6.00007-8

OpenUrl availability

Full text

Cite this

@inbook{a526de1e5dd74b769b3340b1144e13fc,

title = "Emerging strategies in 3D printed tissue models for in vitro biomedical research",

abstract = "3D bioprinting has the potential to provide a unified framework for the manufacturing of tissue models for biomedical research, including drug discovery, disease modeling, and regenerative medicine. However, it remains challenging to 3D print replicas of human tissues that have accurate cell types, cellular densities, extracellular matrix compositions, and that can be assayed in a minimally invasive manner for chronic studies. Here, we review how recent breakthroughs in stem cell biology, tissue engineering, and materials science have led to novel 3D printing strategies that have the potential to solve these challenges.",

author = "Pless, {Christian J.} and Carmen Radeke and Cakal, {Selgin D.} and Janko Kajtez and Pasqualini, {Francesco S.} and Lind, {Johan U.}",

year = "2022",

doi = "10.1016/B978-0-323-85430-6.00007-8",

language = "English",

isbn = "978-0-323-85431-3",

pages = "207--246",

booktitle = "Bioprinting",

publisher = "Elsevier",

address = "United Kingdom",

}

TY - CHAP

T1 - Emerging strategies in 3D printed tissue models for in vitro biomedical research

AU - Pless, Christian J.

AU - Radeke, Carmen

AU - Cakal, Selgin D.

AU - Kajtez, Janko

AU - Pasqualini, Francesco S.

AU - Lind, Johan U.

PY - 2022

Y1 - 2022

N2 - 3D bioprinting has the potential to provide a unified framework for the manufacturing of tissue models for biomedical research, including drug discovery, disease modeling, and regenerative medicine. However, it remains challenging to 3D print replicas of human tissues that have accurate cell types, cellular densities, extracellular matrix compositions, and that can be assayed in a minimally invasive manner for chronic studies. Here, we review how recent breakthroughs in stem cell biology, tissue engineering, and materials science have led to novel 3D printing strategies that have the potential to solve these challenges.

AB - 3D bioprinting has the potential to provide a unified framework for the manufacturing of tissue models for biomedical research, including drug discovery, disease modeling, and regenerative medicine. However, it remains challenging to 3D print replicas of human tissues that have accurate cell types, cellular densities, extracellular matrix compositions, and that can be assayed in a minimally invasive manner for chronic studies. Here, we review how recent breakthroughs in stem cell biology, tissue engineering, and materials science have led to novel 3D printing strategies that have the potential to solve these challenges.

U2 - 10.1016/B978-0-323-85430-6.00007-8

DO - 10.1016/B978-0-323-85430-6.00007-8

M3 - Book chapter

AN - SCOPUS:85137565974

SN - 978-0-323-85431-3

SP - 207

EP - 246

BT - Bioprinting

PB - Elsevier