TY - JOUR
T1 - Electrospun Xanthan gum-Chitosan nanofibers as delivery carrier of hydrophobic bioactives
AU - Shekarforoush, Elhamalsadat
AU - Ajalloueian, Fatemeh
AU - Zeng, Guanghong
AU - Mendes, Ana Carina Loureiro
AU - Chronakis, Ioannis S.
PY - 2018
Y1 - 2018
N2 - Viscoelastic gels of xanthan gum-chitosan(X-Ch) were electrospun to produce nanofibers, stable in aqueous media, for the encapsulation and release of curcumin (Cu). After 120h, the nanofibers released lower amount of curcumin (∼20%) at pH 2.2 comparatively to the release in neutral media (∼50%), suggesting that X-Ch nanofibers could be used as a carrier for the encapsulation of hydrophobic bioactive compounds with long-term pH-stimulated release properties.
AB - Viscoelastic gels of xanthan gum-chitosan(X-Ch) were electrospun to produce nanofibers, stable in aqueous media, for the encapsulation and release of curcumin (Cu). After 120h, the nanofibers released lower amount of curcumin (∼20%) at pH 2.2 comparatively to the release in neutral media (∼50%), suggesting that X-Ch nanofibers could be used as a carrier for the encapsulation of hydrophobic bioactive compounds with long-term pH-stimulated release properties.
KW - Xanthan gum
KW - Chitosan
KW - Electrospinning
KW - Drug delivery
KW - Curcumin
U2 - 10.1016/j.matlet.2018.06.033
DO - 10.1016/j.matlet.2018.06.033
M3 - Journal article
SN - 0167-577X
VL - 228
SP - 322
EP - 326
JO - Materials Letters
JF - Materials Letters
ER -