Electrospun Phospholipid Fibers as Micro-Encapsulation and Antioxidant Matrices

Research output: Contribution to journalJournal articleResearchpeer-review

218 Downloads (Pure)

Abstract

Electrospun phospholipid (asolectin) microfibers were investigated as antioxidants and encapsulation matrices for curcumin and vanillin. These phospholipid microfibers exhibited antioxidant properties which increased after the encapsulation of both curcumin and vanillin. The total antioxidant capacity (TAC) and the total phenolic content (TPC) of curcumin/phospholipid and vanillin/phospholipid microfibers remained stable over time at different temperatures (refrigerated, ambient) and pressures (vacuum, ambient). ¹H-NMR confirmed the chemical stability of both encapsulated curcumin and vanillin within phospholipid fibers. Release studies in aqueous media revealed that the phenolic bioactives were released mainly due to swelling of the phospholipid fiber matrix over time. The above studies confirm the efficacy of electrospun phospholipid microfibers as encapsulation and antioxidant systems.
Original languageEnglish
Article number1708
JournalMolecules
Volume22
Issue number10
Number of pages16
ISSN1420-3049
DOIs
Publication statusPublished - 2017

Keywords

  • antioxidants
  • curcumin
  • electrospinning
  • encapsulation
  • microfibers
  • phospholipids
  • vanillin

Cite this

@article{35e12fba2de04905940601b92b3be1ba,
title = "Electrospun Phospholipid Fibers as Micro-Encapsulation and Antioxidant Matrices",
abstract = "Electrospun phospholipid (asolectin) microfibers were investigated as antioxidants and encapsulation matrices for curcumin and vanillin. These phospholipid microfibers exhibited antioxidant properties which increased after the encapsulation of both curcumin and vanillin. The total antioxidant capacity (TAC) and the total phenolic content (TPC) of curcumin/phospholipid and vanillin/phospholipid microfibers remained stable over time at different temperatures (refrigerated, ambient) and pressures (vacuum, ambient). ¹H-NMR confirmed the chemical stability of both encapsulated curcumin and vanillin within phospholipid fibers. Release studies in aqueous media revealed that the phenolic bioactives were released mainly due to swelling of the phospholipid fiber matrix over time. The above studies confirm the efficacy of electrospun phospholipid microfibers as encapsulation and antioxidant systems.",
keywords = "antioxidants, curcumin, electrospinning, encapsulation, microfibers, phospholipids, vanillin",
author = "Elhamalsadat Shekarforoush and Mendes, {Ana Carina Loureiro} and Vanessa Baj and Beeren, {Sophie R} and Chronakis, {Ioannis S.}",
year = "2017",
doi = "10.3390/molecules22101708",
language = "English",
volume = "22",
journal = "Molecules",
issn = "1420-3049",
publisher = "M D P I AG",
number = "10",

}

Electrospun Phospholipid Fibers as Micro-Encapsulation and Antioxidant Matrices. / Shekarforoush, Elhamalsadat; Mendes, Ana Carina Loureiro; Baj, Vanessa; Beeren, Sophie R; Chronakis, Ioannis S.

In: Molecules, Vol. 22, No. 10, 1708, 2017.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Electrospun Phospholipid Fibers as Micro-Encapsulation and Antioxidant Matrices

AU - Shekarforoush, Elhamalsadat

AU - Mendes, Ana Carina Loureiro

AU - Baj, Vanessa

AU - Beeren, Sophie R

AU - Chronakis, Ioannis S.

PY - 2017

Y1 - 2017

N2 - Electrospun phospholipid (asolectin) microfibers were investigated as antioxidants and encapsulation matrices for curcumin and vanillin. These phospholipid microfibers exhibited antioxidant properties which increased after the encapsulation of both curcumin and vanillin. The total antioxidant capacity (TAC) and the total phenolic content (TPC) of curcumin/phospholipid and vanillin/phospholipid microfibers remained stable over time at different temperatures (refrigerated, ambient) and pressures (vacuum, ambient). ¹H-NMR confirmed the chemical stability of both encapsulated curcumin and vanillin within phospholipid fibers. Release studies in aqueous media revealed that the phenolic bioactives were released mainly due to swelling of the phospholipid fiber matrix over time. The above studies confirm the efficacy of electrospun phospholipid microfibers as encapsulation and antioxidant systems.

AB - Electrospun phospholipid (asolectin) microfibers were investigated as antioxidants and encapsulation matrices for curcumin and vanillin. These phospholipid microfibers exhibited antioxidant properties which increased after the encapsulation of both curcumin and vanillin. The total antioxidant capacity (TAC) and the total phenolic content (TPC) of curcumin/phospholipid and vanillin/phospholipid microfibers remained stable over time at different temperatures (refrigerated, ambient) and pressures (vacuum, ambient). ¹H-NMR confirmed the chemical stability of both encapsulated curcumin and vanillin within phospholipid fibers. Release studies in aqueous media revealed that the phenolic bioactives were released mainly due to swelling of the phospholipid fiber matrix over time. The above studies confirm the efficacy of electrospun phospholipid microfibers as encapsulation and antioxidant systems.

KW - antioxidants

KW - curcumin

KW - electrospinning

KW - encapsulation

KW - microfibers

KW - phospholipids

KW - vanillin

U2 - 10.3390/molecules22101708

DO - 10.3390/molecules22101708

M3 - Journal article

VL - 22

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 10

M1 - 1708

ER -