Electrospray ionization and matrix assisted laser desorption/ionization mass spectrometry: Powerful analytical tools in recombinant protein chemistryPowerful analytical tools in recombinant protein chemistry

J. S. Andersen, Birte Svensson, P. Roepstorff

Research output: Contribution to journalJournal articlepeer-review

Abstract

Electrospray ionization and matrix assisted laser desorption/ionization are effective ionization methods for mass spectrometry of biomolecules. Here we describe the capabilities of these methods for peptide and protein characterization in biotechnology. An integrated analytical strategy is presented encompassing protein characterization prior to and after cloning of the corresponding gene.
Original languageEnglish
JournalNature Biotechnology
Volume14
Issue number4
Pages (from-to)449-457
ISSN1087-0156
DOIs
Publication statusPublished - 1996
Externally publishedYes

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