TY - RPRT
T1 - EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 06, Revision 3 (FGE.06Rev3): Straight- and branched-chain aliphatic unsaturated primary alcohols, aldehydes, carboxylic acids, and esters from chemical groups 1 and 4
AU - EFSA Publication
AU - Larsen, John Christian
AU - Nørby, Karin Kristiane
AU - Beltoft, Vibe Meister
AU - Lund, Pia
AU - Binderup, Mona-Lise
AU - Frandsen, Henrik Lauritz
PY - 2011
Y1 - 2011
N2 - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European
Food Safety Authority was requested to evaluate 50 flavouring substances in the Flavouring Group
Evaluation 6, Revision 3, using the Procedure in Commission Regulation (EC) No 1565/2000. None
of the substances were considered to have genotoxic potential. The substances were evaluated through
a stepwise approach (the Procedure) that integrates information on structure-activity relationships,
intake from current uses, toxicological threshold of concern, and available data on metabolism and
toxicity. The Panel concluded that the 50 substances [FL-no: 02.125, 02.138, 02.152, 02.170, 02.175,
02.176, 02.195, 02.201, 02.222, 02.234, 05.061, 05.082, 05.143, 05.174, 05.203, 05.217, 05.218,
05.220, 05.226, 08.074, 08.100, 08.102, 09.341, 09.368, 09.377, 09.567, 09.569, 09.572, 09.575,
09.612, 09.638, 09.640, 09.643, 09.672, 09.673, 09.674, 09.831, 09.838, 09.884, 09.855, 09.871,
09.872, 09.885, 09.897, 09.898, 09.928, 09.937, 09.938, 09.939 and 09.950] do not give rise to safety
concerns at their levels of dietary intake, estimated on the basis of the MSDI approach. Besides the
safety assessment of these flavouring substances, the specifications for the materials of commerce
have also been considered. For one substance [FL-no: 09.938] an identity test is missing and for two
substances [FL-no: 05.226 and 09.950] the range of the specific gravity is too wide. Additional, the stereoisomeric mixture has not been specified sufficiently for 12 substances [FL-no: 02.152
AB - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European
Food Safety Authority was requested to evaluate 50 flavouring substances in the Flavouring Group
Evaluation 6, Revision 3, using the Procedure in Commission Regulation (EC) No 1565/2000. None
of the substances were considered to have genotoxic potential. The substances were evaluated through
a stepwise approach (the Procedure) that integrates information on structure-activity relationships,
intake from current uses, toxicological threshold of concern, and available data on metabolism and
toxicity. The Panel concluded that the 50 substances [FL-no: 02.125, 02.138, 02.152, 02.170, 02.175,
02.176, 02.195, 02.201, 02.222, 02.234, 05.061, 05.082, 05.143, 05.174, 05.203, 05.217, 05.218,
05.220, 05.226, 08.074, 08.100, 08.102, 09.341, 09.368, 09.377, 09.567, 09.569, 09.572, 09.575,
09.612, 09.638, 09.640, 09.643, 09.672, 09.673, 09.674, 09.831, 09.838, 09.884, 09.855, 09.871,
09.872, 09.885, 09.897, 09.898, 09.928, 09.937, 09.938, 09.939 and 09.950] do not give rise to safety
concerns at their levels of dietary intake, estimated on the basis of the MSDI approach. Besides the
safety assessment of these flavouring substances, the specifications for the materials of commerce
have also been considered. For one substance [FL-no: 09.938] an identity test is missing and for two
substances [FL-no: 05.226 and 09.950] the range of the specific gravity is too wide. Additional, the stereoisomeric mixture has not been specified sufficiently for 12 substances [FL-no: 02.152
U2 - 10.2903/j.efsa.2011.2397
DO - 10.2903/j.efsa.2011.2397
M3 - Report
T3 - the EFSA Journal
BT - EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 06, Revision 3 (FGE.06Rev3): Straight- and branched-chain aliphatic unsaturated primary alcohols, aldehydes, carboxylic acids, and esters from chemical groups 1 and 4
PB - European Food Safety Authority
CY - Parma, Italy
ER -
