Following an application from Dextro Energy GmbH & Co. KG, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Germany, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim related to glucose and “contributes to normal energy-yielding metabolism”. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food constituent that is the subject of the health claim is glucose, which is sufficiently characterised. The claimed effect is “contributes to normal energy-yielding metabolism”. The proposed target population is the general population. Contribution to energy-yielding metabolism is a beneficial physiological effect. A claim on glucose and contribution to energy-yielding metabolism has already been assessed with a favourable outcome.