Efficacy of electrochemically activated water solution in gingivitis treatment

Truong Vo, Dinh-Toi Chu, Duc Duong, Van Bui, Minh Son Tong, Thi Nguyen, Quynh Le, Khanh Hoang Nguyen, Van-Huy Pham, Thien Chu-Dinh*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Mouthwash is one of the most commonly oral healthcare products for prevention and treatment of gum diseases. Dr. ECA is a disinfectant solution manufactured by a Vietnamese company and has been licensed for oral healthcare, but its effect on gingivitis is still unclear. To evaluate the effectiveness of this product in the treatment of gingivitis, we conducted a clinical study in 60 students diagnosed with gingivitis to compare the results of gingivitis treatment using Dr. ECA and a control mouthwash (a demonstrated anti-gingivitis product). The data showed that in the treated group, the rate of good Gingivitis Index (GI) before treatment was 46.67%, but after 2 and 4 weeks of using Dr. ECA that rate was increased to 96.67% and 100%, respectively. The percentage of patients with bleeding on probing was 63.33% but declined sharply after 2 weeks of treatment to 6.67%, and further reduced to 3.33% after 4 weeks of treatment. The treatment outcomes in were similar in the Dr. ECA treated group and control one with no statistically significant difference. Our results suggest that the electrolyte saline solution Dr. ECA is effective in treating gingivitis. Its effects are similar to other mouthwash products that had been approved and marketed.
Original languageEnglish
JournalJournal of Pharmaceutical Investigation
Volume49
Issue number3
Pages (from-to)323-329
ISSN2093-5552
DOIs
Publication statusPublished - 2019

Keywords

  • Biomedicine
  • Biomedicine, general
  • Biomedical and Life Sciences
  • Mouthwash
  • Electrochemically activated water solutions
  • Dr. ECA
  • Gingivitis

Cite this

Vo, T., Chu, D-T., Duong, D., Bui, V., Tong, M. S., Nguyen, T., ... Chu-Dinh, T. (2019). Efficacy of electrochemically activated water solution in gingivitis treatment. Journal of Pharmaceutical Investigation, 49(3), 323-329. https://doi.org/10.1007/s40005-018-00419-7
Vo, Truong ; Chu, Dinh-Toi ; Duong, Duc ; Bui, Van ; Tong, Minh Son ; Nguyen, Thi ; Le, Quynh ; Nguyen, Khanh Hoang ; Pham, Van-Huy ; Chu-Dinh, Thien. / Efficacy of electrochemically activated water solution in gingivitis treatment. In: Journal of Pharmaceutical Investigation. 2019 ; Vol. 49, No. 3. pp. 323-329.
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title = "Efficacy of electrochemically activated water solution in gingivitis treatment",
abstract = "Mouthwash is one of the most commonly oral healthcare products for prevention and treatment of gum diseases. Dr. ECA is a disinfectant solution manufactured by a Vietnamese company and has been licensed for oral healthcare, but its effect on gingivitis is still unclear. To evaluate the effectiveness of this product in the treatment of gingivitis, we conducted a clinical study in 60 students diagnosed with gingivitis to compare the results of gingivitis treatment using Dr. ECA and a control mouthwash (a demonstrated anti-gingivitis product). The data showed that in the treated group, the rate of good Gingivitis Index (GI) before treatment was 46.67{\%}, but after 2 and 4 weeks of using Dr. ECA that rate was increased to 96.67{\%} and 100{\%}, respectively. The percentage of patients with bleeding on probing was 63.33{\%} but declined sharply after 2 weeks of treatment to 6.67{\%}, and further reduced to 3.33{\%} after 4 weeks of treatment. The treatment outcomes in were similar in the Dr. ECA treated group and control one with no statistically significant difference. Our results suggest that the electrolyte saline solution Dr. ECA is effective in treating gingivitis. Its effects are similar to other mouthwash products that had been approved and marketed.",
keywords = "Biomedicine, Biomedicine, general, Biomedical and Life Sciences, Mouthwash, Electrochemically activated water solutions, Dr. ECA, Gingivitis",
author = "Truong Vo and Dinh-Toi Chu and Duc Duong and Van Bui and Tong, {Minh Son} and Thi Nguyen and Quynh Le and Nguyen, {Khanh Hoang} and Van-Huy Pham and Thien Chu-Dinh",
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Vo, T, Chu, D-T, Duong, D, Bui, V, Tong, MS, Nguyen, T, Le, Q, Nguyen, KH, Pham, V-H & Chu-Dinh, T 2019, 'Efficacy of electrochemically activated water solution in gingivitis treatment', Journal of Pharmaceutical Investigation, vol. 49, no. 3, pp. 323-329. https://doi.org/10.1007/s40005-018-00419-7

Efficacy of electrochemically activated water solution in gingivitis treatment. / Vo, Truong; Chu, Dinh-Toi; Duong, Duc; Bui, Van; Tong, Minh Son; Nguyen, Thi; Le, Quynh; Nguyen, Khanh Hoang; Pham, Van-Huy; Chu-Dinh, Thien.

In: Journal of Pharmaceutical Investigation, Vol. 49, No. 3, 2019, p. 323-329.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Efficacy of electrochemically activated water solution in gingivitis treatment

AU - Vo, Truong

AU - Chu, Dinh-Toi

AU - Duong, Duc

AU - Bui, Van

AU - Tong, Minh Son

AU - Nguyen, Thi

AU - Le, Quynh

AU - Nguyen, Khanh Hoang

AU - Pham, Van-Huy

AU - Chu-Dinh, Thien

PY - 2019

Y1 - 2019

N2 - Mouthwash is one of the most commonly oral healthcare products for prevention and treatment of gum diseases. Dr. ECA is a disinfectant solution manufactured by a Vietnamese company and has been licensed for oral healthcare, but its effect on gingivitis is still unclear. To evaluate the effectiveness of this product in the treatment of gingivitis, we conducted a clinical study in 60 students diagnosed with gingivitis to compare the results of gingivitis treatment using Dr. ECA and a control mouthwash (a demonstrated anti-gingivitis product). The data showed that in the treated group, the rate of good Gingivitis Index (GI) before treatment was 46.67%, but after 2 and 4 weeks of using Dr. ECA that rate was increased to 96.67% and 100%, respectively. The percentage of patients with bleeding on probing was 63.33% but declined sharply after 2 weeks of treatment to 6.67%, and further reduced to 3.33% after 4 weeks of treatment. The treatment outcomes in were similar in the Dr. ECA treated group and control one with no statistically significant difference. Our results suggest that the electrolyte saline solution Dr. ECA is effective in treating gingivitis. Its effects are similar to other mouthwash products that had been approved and marketed.

AB - Mouthwash is one of the most commonly oral healthcare products for prevention and treatment of gum diseases. Dr. ECA is a disinfectant solution manufactured by a Vietnamese company and has been licensed for oral healthcare, but its effect on gingivitis is still unclear. To evaluate the effectiveness of this product in the treatment of gingivitis, we conducted a clinical study in 60 students diagnosed with gingivitis to compare the results of gingivitis treatment using Dr. ECA and a control mouthwash (a demonstrated anti-gingivitis product). The data showed that in the treated group, the rate of good Gingivitis Index (GI) before treatment was 46.67%, but after 2 and 4 weeks of using Dr. ECA that rate was increased to 96.67% and 100%, respectively. The percentage of patients with bleeding on probing was 63.33% but declined sharply after 2 weeks of treatment to 6.67%, and further reduced to 3.33% after 4 weeks of treatment. The treatment outcomes in were similar in the Dr. ECA treated group and control one with no statistically significant difference. Our results suggest that the electrolyte saline solution Dr. ECA is effective in treating gingivitis. Its effects are similar to other mouthwash products that had been approved and marketed.

KW - Biomedicine

KW - Biomedicine, general

KW - Biomedical and Life Sciences

KW - Mouthwash

KW - Electrochemically activated water solutions

KW - Dr. ECA

KW - Gingivitis

U2 - 10.1007/s40005-018-00419-7

DO - 10.1007/s40005-018-00419-7

M3 - Journal article

VL - 49

SP - 323

EP - 329

JO - Journal of Pharmaceutical Investigation

JF - Journal of Pharmaceutical Investigation

SN - 2093-5552

IS - 3

ER -