TY - JOUR
T1 - Effect of Whole-Body X-Irradiation of the Synthesis of Individual Fatty Acids in Liver Slices from Normal and Fasted Rats
AU - Hansen, Heinz Johs. Max
AU - Hansen, Lisbeth Grænge
AU - Faber, M.
PY - 1965
Y1 - 1965
N2 - (1) Using (2-14C) acetate and (1-14C) butyrate as precursors, rat-liver fatty acids were synthesized in vitro and assayed by paper chromatography.
(2) Whole-body x-irradiation induced a change in the synthetic pattern of hepatic fatty acids towards a relatively enhanced synthesis of palmitic acid.
(3) X-irradiation and fasting seem to have opposite effects on fatty-acid synthesis. X-irradiation counteracts the drop in total synthesis and the relatively enhanced synthesis of palmitoleic acid induced by fasting. The relative enhancement of palmitic-acid synthesis mentioned under (2) stands in contrast to the effect of fasting, which specifically decreases the hepatic synthesis of palmitic acid.
(4) There is a general similarity between corresponding fatty-acid patterns based on synthesis from (2-14C) acetate and (1-14C) butyrate, respectively.
AB - (1) Using (2-14C) acetate and (1-14C) butyrate as precursors, rat-liver fatty acids were synthesized in vitro and assayed by paper chromatography.
(2) Whole-body x-irradiation induced a change in the synthetic pattern of hepatic fatty acids towards a relatively enhanced synthesis of palmitic acid.
(3) X-irradiation and fasting seem to have opposite effects on fatty-acid synthesis. X-irradiation counteracts the drop in total synthesis and the relatively enhanced synthesis of palmitoleic acid induced by fasting. The relative enhancement of palmitic-acid synthesis mentioned under (2) stands in contrast to the effect of fasting, which specifically decreases the hepatic synthesis of palmitic acid.
(4) There is a general similarity between corresponding fatty-acid patterns based on synthesis from (2-14C) acetate and (1-14C) butyrate, respectively.
U2 - 10.1080/09553006514550031
DO - 10.1080/09553006514550031
M3 - Journal article
VL - 9
SP - 25
EP - 36
JO - International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
JF - International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
IS - 1
ER -