To improve the expression and secretion of heterologous proteins in the filamentous grampositive bacteria, Streptomyces lividans, bioprocessing strategies were developed. A mathematical model was constructed to study the effects of the process kinetic parameters on the production of the model-protein RFP. The model describes the dynamics of glucose consumption and formation of biomass in addition to RFP production. The model was also extended to describe a two substrate condition.
|Publication status||Published - 2011|
|Event||6th Danish Conference on Biotechnology and Molecular Biology: Synthetic Biology and Cell Factories - Vejle, Denmark|
Duration: 26 May 2011 → 27 May 2011
Conference number: 6
|Conference||6th Danish Conference on Biotechnology and Molecular Biology|
|Period||26/05/2011 → 27/05/2011|