Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci

Fan Han; Minal Jamsandekar; Mats E. Pettersson; Leyi Su; Angela Fuentes-Pardo; Brian Davis; Dorte Bekkevold; Florian Berg; Michele Casini; Geir Dahle; Edward D. Farrell; Arild Folkvord; Leif Andersson

doi:10.7554/eLife.61076

Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci

Fan Han, Minal Jamsandekar, Mats E. Pettersson, Leyi Su, Angela Fuentes-Pardo, Brian Davis, Dorte Bekkevold, Florian Berg, Michele Casini, Geir Dahle, Edward D. Farrell, Arild Folkvord, Leif Andersson^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

Atlantic herring is widespread in North Atlantic and adjacent waters and is one of the most abundant vertebrates on earth. This species is well suited to explore genetic adaptation due to minute genetic differentiation at selectively neutral loci. Here we report hundreds of loci underlying ecological adaptation to different geographic areas and spawning conditions. Four of these represent megabase inversions confirmed by long read sequencing. The genetic architecture underlying ecological adaptation in herring deviates from expectation under a classical infinitesimal model for complex traits because of large shifts in allele frequencies at hundreds of loci under selection.

Original language	English
Article number	e61076
Journal	eLife
Volume	9
Number of pages	20
ISSN	2050-084X
DOIs	https://doi.org/10.7554/eLife.61076
Publication status	Published - 2020

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10.7554/eLife.61076

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PELA: Pelagic species (39698/102139)
Jensen, G. H. (Project Coordinator), van Deurs, M. S. K. (Project Manager), Munk, P. (Project Manager), Bekkevold, D. (Project Manager), Storr-Paulsen, M. (Project Manager), Henriksen, O. (Project Participant), Behrens, J. (Project Participant), Davies, J. O. (Project Participant), Andreasen, H. (Project Participant), Albertsen, C. M. (Project Participant), Huwer, B. (Project Participant), Jacobsen, L. M. W. (Project Participant), Håkansson, K. B. (Project Participant), Berg, C. W. (Project Participant), Mosegaard, H. (Project Participant) & Trijoulet, V. (PI)
14/06/2019 → 20/09/2021
Project: Research

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title = "Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci",

abstract = "Atlantic herring is widespread in North Atlantic and adjacent waters and is one of the most abundant vertebrates on earth. This species is well suited to explore genetic adaptation due to minute genetic differentiation at selectively neutral loci. Here we report hundreds of loci underlying ecological adaptation to different geographic areas and spawning conditions. Four of these represent megabase inversions confirmed by long read sequencing. The genetic architecture underlying ecological adaptation in herring deviates from expectation under a classical infinitesimal model for complex traits because of large shifts in allele frequencies at hundreds of loci under selection.",

author = "Fan Han and Minal Jamsandekar and Pettersson, {Mats E.} and Leyi Su and Angela Fuentes-Pardo and Brian Davis and Dorte Bekkevold and Florian Berg and Michele Casini and Geir Dahle and Farrell, {Edward D.} and Arild Folkvord and Leif Andersson",

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T1 - Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci

AU - Han, Fan

AU - Jamsandekar, Minal

AU - Pettersson, Mats E.

AU - Su, Leyi

AU - Fuentes-Pardo, Angela

AU - Davis, Brian

AU - Bekkevold, Dorte

AU - Berg, Florian

AU - Casini, Michele

AU - Dahle, Geir

AU - Farrell, Edward D.

AU - Folkvord, Arild

AU - Andersson, Leif

PY - 2020

Y1 - 2020

N2 - Atlantic herring is widespread in North Atlantic and adjacent waters and is one of the most abundant vertebrates on earth. This species is well suited to explore genetic adaptation due to minute genetic differentiation at selectively neutral loci. Here we report hundreds of loci underlying ecological adaptation to different geographic areas and spawning conditions. Four of these represent megabase inversions confirmed by long read sequencing. The genetic architecture underlying ecological adaptation in herring deviates from expectation under a classical infinitesimal model for complex traits because of large shifts in allele frequencies at hundreds of loci under selection.

AB - Atlantic herring is widespread in North Atlantic and adjacent waters and is one of the most abundant vertebrates on earth. This species is well suited to explore genetic adaptation due to minute genetic differentiation at selectively neutral loci. Here we report hundreds of loci underlying ecological adaptation to different geographic areas and spawning conditions. Four of these represent megabase inversions confirmed by long read sequencing. The genetic architecture underlying ecological adaptation in herring deviates from expectation under a classical infinitesimal model for complex traits because of large shifts in allele frequencies at hundreds of loci under selection.

U2 - 10.7554/eLife.61076

DO - 10.7554/eLife.61076

M3 - Journal article

C2 - 33274714

SN - 2050-084X

VL - 9

JO - eLife

JF - eLife

M1 - e61076

ER -

Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci

Abstract

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PELA: Pelagic species (39698/102139)

Cite this